ࡱ> ^_`a l \pThe Free Software Foundation B=PF0*8X@"1 Helvetica1Courier1 Courier New1 Courier New1 Helvetica$#,##0_);($#,##0)$#,##0_);[Red]($#,##0)$#,##0.00_);($#,##0.00)$#,##0.00_);[Red]($#,##0.00)-**_($* #,##0_);_($* (#,##0);_($* "-"_);_(@_)*)'_(* #,##0_);_(* (#,##0);_(* "-"_);_(@_)5,2_($* #,##0.00_);_($* (#,##0.00);_($* "-"??_);_(@_)2+/_(* #,##0.00_);_(* (#,##0.00);_(* "-"??_);_(@_)2$#,##0.00;[Red]$#,##0.003$#,##0.00;[Red]($#,##0.00)4$#,##0;[Red]($#,##00)50.00%;[Red](0.00%)6 0%;[Red](0%)7#,##0.00;[Red](#,##0.00)8#,##0;[Red](#,##0)                + ) , *   Ј ~~ ؈ ~~#؈ ~~ ؈ ~~3#܈ ~~4#܈ ~~8#܈ ~~9#܈ ~~83ffff̙̙3f3fff3f3f33333f33&) Neither the Securities and Exch PROSPECTUS$PROSPECTUS (1)1PROSPECTUS (2)<PROSPECTUS (3)\Company Information zCompany Information (1)&/Our stock price can be volatile&We will require additional capi&˭We will require additional (1)Fees and Expenses,LockUp AgreementsREXPERTS&fNeither the Securities and (1)&.Our stock price can be vola (1)&Our existing and future collabo&wOur existing and future col (1)&3RATIO OF EARNINGS TO FIXED CHARAPreferred StocknKPreferred Stock (1)]Preferred Stock (2)g Delaware Law-wGeneralA General (1) General (2)&Denomination Interest Registrat&Merger Consolidation or Sale of&QEvents of Default Notice and Wa&\Events of Default Notice an (1)&Events of Default Notice an (2)%XModification of the Indentures%5Modification of the Indent (1) OVoting&aDischarge Defeasance and CovenaCoDESCRIPTION OF WARRANTS"DESCRIPTION OF WARRANTS (1)"sDESCRIPTION OF WARRANTS (2)"BookEntry Delivery and Form&8BookEntry Delivery and Form (1)tPLAN OF DISTRIBUTION l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??' PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } -} $                     Advaxis, Inc. 424B5 01/21/2020jbNeither the Securities and Exchange Commission nor any state securities commission has approved or Per share Total        Public offering price  ?  ~ ހ  Placement agent fees (1)  Fx?  ~ ) - %Proceeds to Advaxis (before expenses)  "~j?  ~ r6W  $____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/( TF:."l=PF0*8X> @Z        l  #  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and ExchPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } 1}        Advaxis, Inc. 424B5 01/21/2020 PROSPECTUS Page(  ABOUT THIS PROSPECTUS SUPPLEMENT i1 )SPECIAL CAUTIONARY NOTE REGARDING FORWARD ii LOOKING STATEMENTS% PROSPECTUS SUPPLEMENT SUMMARY S-1  THE OFFERING S-3 RISK FACTORS S-4USE OF PROCEEDS S-8DIVIDEND POLICY S-9DILUTION S-10%PRIVATE PLACEMENT TRANSACTION S-11PLAN OF DISTRIBUTION S-12 LEGAL MATTERS S-14EXPERTS S-14+#WHERE YOU CAN FIND MORE INFORMATION S-14,$INCORPORATION OF CERTAIN INFORMATION S-14 BY REFERENCE$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/>g0z^%e>]4znF=PF0*8X> @ l  !0R1  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } 1}  !      Advaxis, Inc. 424B5 01/21/2020 PROSPECTUS Page About this Prospectus~ + #Where You Can Find More Information~  , $Incorporation of Certain Information~    by Reference  Risk Factors~ 1)Special Cautionary Note Regarding Forward~ "Looking Statements Advaxis, Inc.~ &Use of Proceeds~ 6*"Ratio of Earnings to Fixed Charges~ :Securities We May Offer~ >$Description of Capital Stock~ B&Description of Debt Securities~ NDescription of Warrants~ vDescription of Units~ zGlobal Securities~ ~Plan of Distribution~  Legal Matters~ Experts~ $____________________________1)Created by Morningstar Document Research.D lz^/v3X"`2  0 (http://documentresearch.morningstar.com/H=PF0*8X> @  l  7<  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 7       Advaxis, Inc. 424B5 01/21/2020 PROSPECTUS ?6.the success and timing of our clinical trials,  " including patient accrual;     ?3 +our ability to continue as a going concern;     ?5 -our ability to obtain and maintain regulatory4,approval and/or reimbursement of our product!candidates for marketing;$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/.z'uQrfZ2=PF0*8X> @ l  U7KUG\  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} I; U      Advaxis, Inc. 424B5 01/21/2020 PROSPECTUS ?6.our ability to obtain the appropriate labeling  6 .of our products under any regulatory approval;     ?. &our plans to develop and commercialize    our products;    ?5-the successful development and implementation0(of future sales and marketing campaigns; ?2*the change of key scientific or management personnel; ?4,the size and growth of the potential markets2*for our product candidates and our abilityto serve those markets; ?.&our ability to successfully compete in91the potential markets for our product candidates,if commercialized; ?-%regulatory developments in the United%States and foreign countries; ?0(the rate and degree of market acceptanceDlz'f5sO]el+ !"#$%&'()*+,-./0123456789:;<=>?  ) !of any of our product candidates;!!!" "?/"'new products, product candidates or new##2#*uses for existing products or technologies$$2$*introduced or announced by our competitors%%0%(and the timing of these introductions or&&&announcements;'''( (?/('market conditions in the pharmaceutical))")and biotechnology sectors;***+ +?+our available cash;,,,- -?/-'the accuracy of our estimates regarding..7./expenses, future revenues, capital requirements//+/#and needs for additional financing;0001 1?11)our ability to obtain additional funding;2223 3?73/our ability to obtain and maintain intellectual4474/property protection for our product candidates;5556 6?06(the ability of our product candidates to77/7'successfully perform in clinical trials8828*and to resolve any clinical holds that may999occur;:::; ;?3;+our ability to obtain and maintain approval<<7</of our product candidates for trial initiation;===> >?6>.our ability to manufacture and the performance??%?of third-party manufacturers;DS lKc1 _'d3o$8@ABCDEFGHIJKLMNOPQRST@@@A A?9A1our ability to identify license and collaborationBB8B0partners and to maintain existing relationships;CCCD D?0D(the performance of our clinical researchEE.E&organizations, clinical trial sponsorsFF-F%and clinical trial investigators, andGG/G'collaboration partners for any clinicalHHHtrials we conduct;IIIJ J?-J%our ability to successfully implementKKKour strategy; andLLLM M?2M*our ability to maintain the listing of ourNN0N(common stock on the Nasdaq Global SelectOOOMarket.PQ$R____________________________1S)Created by Morningstar Document Research.0T(http://documentresearch.morningstar.com/.-2w.? K =PF0*8X> @TTSSRR l  F lwy  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } 2} $ } : F      Advaxis, Inc. 424B5 01/21/2020Company Information"Common stock offered by us10,000,000 shares   2 *Common stock to be outstanding immediately  60,221,263 shares after the offering    Offering Price  $1.05 per shareUse of proceeds5-We expect the net proceeds from this offering0(will be approximately $9.6 million after/'deducting the discounts and commissions5-and estimated offering expenses and estimated5-offering expenses payable by us, as described/'in ?Plan of Distribution,? on page S-120(of this prospectus supplement. We intend2*to use the net proceeds from this offering6.to fund our continued research and development2*initiatives in connection with our product/'pipeline including, but not limited to,1)in our ADXS-HOT program and potential new0(studies for our ADXS-PSA drug candidate,+#and for general corporate purposes.1)See ?Use of Proceeds? on page S-8 of this1)prospectus supplement for a more completeD l}q"]L_z(B !"#$%&'()*+,-./0123456789:;<=>?  3 +description of the intended use of proceeds!!!from this offering."""# Best Efforts#3#+We have agreed to issue and sell the shares$$4$,of common stock offered hereby to the public%%6%.through the placement agent, and the placement&&6&.agent has agreed to offer and sell such shares''0'(on a ?best efforts? basis. The placement((2(*agent is not required to sell any specific))0)(number or dollar amount of the shares of**1*)common stock offered hereby, but will use++1+)its best efforts to sell such securities.,,/,'See ?Plan of Distribution? on page S-12--&-of this prospectus supplement..../ Risk factors/8/0Investing in our securities involves significant0040,risks. Please read the information contained1111)in or incorporated by reference under the2202(heading ?Risk Factors? beginning on page33.3&S-4 of this prospectus supplement, and44840under similar headings in documents incorporated5545,by reference into this prospectus supplement66(6 and the accompanying prospectus.777*8"Nasdaq Global Select Market symbol88?ADXS.?999%:Private Placement Transaction:5:-In a concurrent private placement transaction;;-;%(the ?Private Placement Transaction?)<<3<+we intend to sell to the purchasers in this==2=*offering unregistered warrants to purchase>>3>+50% of the shares of common stock purchased??0?(in this offering. See ?Private PlacementD lzVYm! @EEDDCC l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company Information!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 6       Advaxis, Inc. 424B5 01/21/2020Company Information ?3+420,726 shares of our common stock reserved  5 -for issuance upon the exercise of outstanding  / 'warrants at a weighted average exercise  ! price of $0.08 per share;     ?2 *11,982 shares of our common stock reserved2*for issuance upon settlement of restricted stock units; ?3+554,005 shares of our common stock reserved5-for issuance upon the exercise of outstanding4,stock options at a weighted average exercise&price of $72.10 per share; and ?2*32,216 shares of our common stock reserved2*for future awards under our 2015 Incentive Plan.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/@D}q!H$W3B? =PF0*8X> @ l  >+U  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} > >      Advaxis, Inc. 424B5 01/21/2020kcOur stock price can be volatile, which increases the risk of litigation, and may result in a signif ?/'changes in the market valuations, stock  4 ,market prices and trading volumes of similar    companies;     ?0 (actual or anticipated changes in our net  5 -loss or fluctuations in our operating results6.or in the expectations of securities analysts; ?6.the issuance of new equity securities pursuant1)to a future offering, including potential%issuances of preferred stock; ?+#sales of large blocks of our stock; ?/'failure of our common stock or warrants2*to be listed or quoted on the Nasdaq Stock4,Market, NYSE Amex Equities or other nationalmarket system; ?1)additions or departures of key personnel; ?/'changes in the regulatory status of our-%immunotherapies, including results of-%our pre-clinical and clinical trials;Db lE9-!W3C>bn  !"#$%&'()*+,-./0123456789:;<=   ! !?-!%regulatory developments in the United""#"States and other countries;###$ $?6$.positive and negative changes in relationships%%%with partners;&&&' '?7'/events affecting the University of Pennsylvania((<(4or any of our other current or future collaborators;)))* *?6*.announcements of new products or technologies,++0+(commercial relationships or other events,,!,by us or our competitors;---. .?).!changes in accounting principles;///0 0?20*discussion of us or our stock price by the1141,financial and scientific press and in online222investor communities;3334 4?:42market conditions and events in the pharmaceutical55 5and biotech sectors; and6667 7?.7&general economic, industry, and market888 conditions.9:$;____________________________1<)Created by Morningstar Document Research.0=(http://documentresearch.morningstar.com/@DS/2cpLtPN=PF0*8X> @==<<;; l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } 8} $                         Advaxis, Inc. 424B5 01/21/2020kcWe will require additional capital funding, the receipt of which may impair the value of our common'Public offering price per share?7 /Net tangible book value per share as of January  Q?      7, 2020. &Increase per share attributable to new  )\(?       investors/ 'As adjusted net tangible book value per      q= ףp? 1)share as of January 7, 2020, after givingeffect to this offering6.Dilution per share to new investors purchasingRQ?shares in this offering$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/0E9-!hSn=PF0*8X> @B    l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capiFees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 6       Advaxis, Inc. 424B5 01/21/2020kcWe will require additional capital funding, the receipt of which may impair the value of our common ?3+420,726 shares of our common stock reserved  5 -for issuance upon the exercise of outstanding  / 'warrants at a weighted average exercise  ! price of $0.08 per share;  ?2 *11,982 shares of our common stock reserved  2 *for issuance upon settlement of restricted stock units; ?3+554,005 shares of our common stock reserved5-for issuance upon the exercise of outstanding4,stock options at a weighted average exercise&price of $72.10 per share; and ?2*32,216 shares of our common stock reserved2*for future awards under our 2015 Incentive Plan.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/:E9-!5[+:[2&=PF0*8X> @ l  i  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)LockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } '} $                    Advaxis, Inc. 424B5 01/21/2020Fees and Expenses. Per Share Total Public offering price  ?  ~ ހ  Placement agent fees  Fx?  ~ ) (  Proceeds, before expenses, to us  "~j?  ~ r6W   $____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/&J@~r/s=PF0*8X> @Z        l  "  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and Expenses EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 6 "      Advaxis, Inc. 424B5 01/21/2020Lock-Up Agreements. ?1)sell, offer, contract or grant any option  3 +to sell (including any short sale), pledge,  3 +transfer, establish an open ?put equivalent  5 -position? within the meaning of Rule 16a-l(h)  2 *under the Securities Exchange Act of 1934,    as amended; ?0(enter into any swap or other arrangement1)that transfers to another, in whole or in.&part, any of the economic consequences/'of ownership of our securities, whether0(any such transaction is to be settled by/'delivery of our shares of common stock,in cash or otherwise; ?1)make any demand for or exercise any right/'with respect to the registration of anyof our securities; or ?/'publicly disclose the intention to make/'any offer, sale, pledge or disposition,/'or to enter into any transaction, swap,.&hedge or other arrangement relating toany of our securities.$____________________________D@ l}q#4j @!!  l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 6       Advaxis, Inc. 424B5 01/21/2020EXPERTS ?5-our Annual Report on Form 10-K for the fiscal  / 'year ended October 31, 2019, filed with  0 (the SEC on December 20, 2019, as amended   on January 21, 2020;  ?2 *our Current Reports on Form 8-K filed with  2 *the SEC on January 7, 2020 and January 16, 2020; and ?0(the description of our common stock, par0(value $0.001 per share, contained in our1)Registration Statement on Form 8-A, filed0(with the Commission on October 15, 2013,/'and all amendments and reports updatingsuch description.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/8}+\ E`=PF0*8X> @ l  !;  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } 1} $ }  !      Advaxis, Inc. 424B5 01/21/2020jbNeither the Securities and Exchange Commission nor any state securities commission has approved or Page About this Prospectus ~ + #Where You Can Find More Information ~  , $Incorporation of Certain Information ~    by Reference  Risk Factors ~ 1)Special Cautionary Note Regarding Forward~ "Looking Statements Advaxis, Inc.~ &Use of Proceeds~ 6*"Ratio of Earnings to Fixed Charges~ :Securities We May Offer~ >$Description of Capital Stock~ B&Description of Debt Securities~ NDescription of Warrants~ vDescription of Units~ zGlobal Securities~ ~Plan of Distribution~  Legal Matters~ Experts~ $____________________________1)Created by Morningstar Document Research.D;lF:."v,uB FT 0 (http://documentresearch.morningstar.com/H=PF0*8X> @  l  3g  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} > 3      Advaxis, Inc. 424B5 01/21/2020kcOur stock price can be volatile, which increases the risk of litigation, and may result in a signif ?4,price and volume fluctuations in the overall  ' stock market from time to time;  ?/ 'changes in the market valuations, stock  4 ,market prices and trading volumes of similar    companies;  ?0 (actual or anticipated changes in our net5-loss or fluctuations in our operating results6.or in the expectations of securities analysts; ?6.the issuance of new equity securities pursuant1)to a future offering, including potential%issuances of preferred stock; ?/'general economic conditions and trends; ?-%positive and negative events relating4,to healthcare and the overall pharmaceuticaland biotech sector; ?"major catastrophic events; ?+#sales of large blocks of our stock; ?1)additions or departures of key personnel; ?/'changes in the regulatory status of our-%immunotherapies, including results of-%our pre-clinical and clinical trials; ?6.positive and negative changes in relationshipswith partners; ?7/events affecting the University of PennsylvaniaD7 lE9-!Av%3\ Nk" !"#$%&'()*+,-./012  < 4or any of our other current or future collaborators;! !?6!.announcements of new products or technologies,""0"(commercial relationships or other events##!#by us or our competitors;$ $?-$%regulatory developments in the United%%#%States and other countries;& &?/&'failure of our common stock or warrants''2'*to be listed or quoted on the Nasdaq Stock((4(,Market, NYSE Amex Equities or other national)))market system;* *?-*%changes in accounting principles; and+ +?2+*discussion of us or our stock price by the,,4,,financial and scientific press and in online---investor communities../$0____________________________11)Created by Morningstar Document Research.02(http://documentresearch.morningstar.com/* hU CY'>=PF0*8X> @221100 l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} :       Advaxis, Inc. 424B5 01/21/2020kcOur existing and future collaborations are important to our business. If we are unable to establish ?7/significant time and effort from our management   team;  ?8 0financial funding to support said collaboration;  ?4 ,coordination of our research and development  2 *programs with the research and development  , $priorities of our collaborators; and ?-%effective allocation of our resourcesto multiple projects.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/.hE9-!Oh=PF0*8X> @ l  H$0'3  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $}  @ H      Advaxis, Inc. 424B5 01/21/2020kcOur existing and future collaborations are important to our business. If we are unable to establish ?/'we will not directly control the amount  ; 3or timing of resources devoted by our collaborators  5 -to activities related to our immunotherapies;  ?3 +our collaborators may not commit sufficient  1 )resources to our research and development  4 ,programs or the commercialization, marketing/'or distribution of our immunotherapies; ?/'our collaborators may not perform their obligations as expected; ?1)our collaborators may fail to comply with4,applicable regulatory requirements regarding2*the development, manufacture, distribution7/or marketing of a product candidate or product; ?-%our collaborators may pursue existing.&or other development-stage products or.&alternative technologies in preference1)to those being developed in collaborationwith us; ?-%our collaborators could independently/'develop, or develop with third parties,4,products that compete directly or indirectly1)with our products and product candidates,91or product candidates discovered in collaboration2*with us may be viewed by our collaboratorsD~ lE9-!~-@m.PB !"#$%&'()*+,-./0123456789:;<=>?  8 0as competitive with their own product candidates!!3!+or products, which in either case may cause""6".our collaborators to cease to devote resources###to us;$ $?0$(if we fail to make required milestone or%%-%%royalty payments to our collaborators&&9&1or to observe other obligations in our agreements''1')with them, our collaborators may have the((,($right to terminate those agreements;) )?1))our collaborators may seek to renegotiate**/*'agreements we have entered into, or may++;+3disagree with us about the terms and implementation,,,of these agreements;- -?--%disagreements with our collaborators,..0.(including disagreements over proprietary//./&rights, contract interpretation or the00.0&preferred course of development, might1151-cause delays or terminations of the research,2232+development or commercialization of product33=35candidates, might lead to additional responsibilities4424*for us with respect to product candidates,5555-or might result in litigation or arbitration,6606(any of which would be time-consuming and777 expensive;8 8?38+our collaborators may not properly maintain9929*or defend our intellectual property rights::.:&or may use our proprietary information;;3;+in a manner that may invite litigation that<<7</could jeopardize or invalidate our intellectual==.=&property or proprietary information or>>.>&expose us to potential litigation; and? ??7?/our collaborators may infringe the intellectualD l] Kaq9Yow+_s)@ABCDEFG@@/@'property rights of third parties, whichAA1A)may expose us to litigation and potentialBBB liability.CD$E____________________________1F)Created by Morningstar Document Research.0G(http://documentresearch.morningstar.com/h:."=PF0*8X> @GGFFEE l  A  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)Preferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } 1} $ }  } $ }  }  $ } } $ }  } $ }  } $ } m} $       Advaxis, Inc. 424B5 01/21/2020*"RATIO OF EARNINGS TO FIXED CHARGESYears Ended October 31, Nine Months                        Ended   ~    ~    ~ ~   ~ z   ~ v     July 31, 2018 1 )Ratio of earnings (loss) to fixed charges   N/A    N/A    N/A    N/A    N/A    N/A   $____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/&(@znb<=PF0*8X> @" l  J  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 6       Advaxis, Inc. 424B5 01/21/2020Preferred Stock ?#the title and stated value;  ?5 -the number of shares offered, the liquidation  4 ,preference per share and the purchase price;  ?- %the liquidation preference per share;  $____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/&@u5I=1 =PF0*8X> @ l  &[\  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} = &      Advaxis, Inc. 424B5 01/21/2020Preferred Stock ?.&the dividend rate(s), period(s) and/or  4 ,payment date(s), or method(s) of calculation   for such dividends;  ?/ 'whether dividends will be cumulative or  . &non-cumulative and, if cumulative, the  2 *date from which dividends will accumulate; ?7/the procedures for any auction and remarketing,if any; ?2*the provisions for a sinking fund, if any; ?4,the provisions for redemption or repurchase,.&if applicable, and any restrictions on0(our ability to exercise those redemptionand repurchase rights; ?1)any listing of the preferred stock on any&securities exchange or market; ?7/whether the preferred stock will be convertible2*into our common stock, and, if applicable,;3the conversion price (or how it will be calculated)and conversion period; ?80whether the preferred stock will be exchangeable1)into debt securities, and, if applicable,91the exchange price (or how it will be calculated)and exchange period; ?/'voting rights, if any, of the preferredD lu*W k@V @G k !"#$%   stock;!"$#____________________________1$)Created by Morningstar Document Research.0%(http://documentresearch.morningstar.com/Kd=PF0*8X> @%%$$## l  Eg  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} $4       Advaxis, Inc. 424B5 01/21/2020Preferred Stock ?3+preemptive rights, if any, of the preferred   stock;  ?3 +a discussion of any material and/or special  . &U.S. federal income tax considerations  * "applicable to the preferred stock;  ?/ 'restrictions on transfer, sale or otherassignment, if any;$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/,|u%aX=PF0*8X> @ l  v  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} =       Advaxis, Inc. 424B5 01/21/2020 Delaware Law ?-%any merger or consolidation involving  7 /the corporation and the interested stockholder;  ?7 /any sale, transfer, pledge or other disposition  7 /of 10% or more of the assets of the corporation  - %involving the interested stockholder;  ?6 .subject to certain exceptions, any transaction0(that results in the issuance or transfer:2by the corporation of any stock of the corporation&to the interested stockholder; ?1)any transaction involving the corporation;3that has the effect of increasing the proportionate1)share of the stock of any class or series-%of the corporation beneficially owned)!by the interested stockholder; or ?1)the receipt by the interested stockholder:2of the benefit of any loans, advances, guarantees,4,pledges or other financial benefits provided&by or through the corporation.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/B Xx.4Lfy4@=PF0*8X> @ l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 8       Advaxis, Inc. 424B5 01/21/2020General ?2*do not limit the amount of debt securities   that we may issue;  ?0 (allow us to issue debt securities in one   or more series;  ?2 *do not require us to issue all of the debt  0 (securities of a series at the same time; ?7/allow us to reopen a series to issue additional.&debt securities without the consent of2*the holders of the debt securities of such series; and ?0(provide that the debt securities will be0(unsecured, except as may be set forth in-%the applicable prospectus supplement.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/8}.x)?u)=PF0*8X> @ l   4Bs  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} =       Advaxis, Inc. 424B5 01/21/2020General ?4,the title of the debt securities and whether  (  they are senior or subordinated;  ?2 *the aggregate principal amount of the debt  / 'securities being offered, the aggregate  / 'principal amount of the debt securities  5 -outstanding as of the most recent practicable7/date and any limit on their aggregate principal1)amount, including the aggregate principal-%amount of debt securities authorized; ?3+the price at which the debt securities will/'be issued, expressed as a percentage of6.the principal and, if other than the principal4,amount thereof, the portion of the principal/'amount thereof payable upon declaration/'of acceleration of the maturity thereof7/or, if applicable, the portion of the principal:2amount of such debt securities that is convertible0(into common stock or other securities of4,ours or the method by which any such portionshall be determined; ?/'if convertible, the terms on which such2*debt securities are convertible, including0(the initial conversion price or rate and0(the conversion period and any applicableD9 l},N_y.AMy- !"#$%&'()*+,-./0123456789:;<=>?  7 /limitations on the ownership or transferability!!3!+of common stock or other securities of ours"""received on conversion;# #?8#0the date or dates, or the method for determining$$1$)the date or dates, on which the principal%%/%'of the debt securities will be payable;& &?4&,the fixed or variable interest rate or rates''0'(of the debt securities, or the method by((7(/which the interest rate or rates is determined;) )?8)0the date or dates, or the method for determining**3*+the date or dates, from which interest will+++accrue;, ,?4,,the dates on which interest will be payable;- -?4-,the record dates for interest payment dates,..1.)or the method by which such dates will be/// determined;0 0?50-the persons to whom interest will be payable;1 1?810the basis upon which interest will be calculated2262.if other than that of a 360-day year of twelve33330-day months;4 4?24*any make-whole amount, which is the amount5525*in addition to principal and interest that6666.is required to be paid to the holder of a debt7777/security as a result of any optional redemption8858-or accelerated payment of such debt security,9949,or the method for determining the make-whole:::amount;; ;?/;'the place or places where the principal<<1<)of, and any premium or make-whole amount,==1=)and interest on, the debt securities will>>> be payable;? ??4?,where the debt securities may be surrenderedD l^#6Fw&Y`.?K :@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_@@2@*for registration of transfer or conversionAAA or exchange;B B?1B)where notices or demands to or upon us inCC9C1respect of the debt securities and the applicableDD Dindenture may be served;E E?8E0the times, prices and other terms and conditionsFF5F-upon which we may redeem the debt securities;G G?/G'any obligation we have to redeem, repayHH0H(or purchase the debt securities pursuantII2I*to any sinking fund or analogous provisionJJ;J3or at the option of holders of the debt securities,KK1K)and the times and prices at which we mustLL5L-redeem, repay or purchase the debt securitiesMM'Mas a result of such obligation;N N?/N'the currency or currencies in which theOO3O+debt securities are denominated and payablePP0P(if other than U.S. dollars, which may beQQ2Q*a foreign currency or units of two or moreRR2R*foreign currencies or a composite currencySS2S*or currencies and the terms and conditionsTT7T/relating thereto, and the manner of determiningUU/U'the equivalent of such foreign currencyVVVin U.S. dollars;W W?1W)whether the principal of, and any premiumXX1X)or make-whole amount, or interest on, theYY8Y0debt securities of the series are to be payable,ZZ7Z/at our election or at the election of a holder,[[3[+in a currency or currencies other than that\\4\,in which the debt securities are denominated]]2]*or stated to be payable, and other related^^^terms and conditions;_ _?3_+whether the amount of payments of principalD l4Nes"D\pj~-.&interests for other debt securities of4,the series, and the manner in which interestshall be paid; ?5-the identity of the depositary for securities1)in registered form, if such series are to)!be issuable as a global security; ?0(the date as of which any debt securities2*in bearer form or in temporary global form1)shall be dated if other than the original2*issuance date of the first security of theseries to be issued; ?4,the applicability, if any, of the defeasance4,and covenant defeasance provisions described/'in this prospectus or in the applicable indenture;$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/,q|f4PhA=PF0*8X> @ l  ;G  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} y< ;      Advaxis, Inc. 424B5 01/21/2020General ?/'whether and under what circumstances we  3 +will pay any additional amounts on the debt  4 ,securities in respect of any tax, assessment  2 *or governmental charge and, if so, whether  2 *we will have the option to redeem the debt  4 ,securities in lieu of making such a payment; ?0(whether and under what circumstances the5-debt securities being offered are convertible0(into common stock or other securities of:2ours, as the case may be, including the conversion3+price or rate and the manner or calculationthereof; ?/'the circumstances, if any, specified in-%the applicable prospectus supplement,2*under which beneficial owners of interests4,in the global security may obtain definitive/'debt securities and the manner in which4,payments on a permanent global debt security80will be made if any debt securities are issuable.&in temporary or permanent global form; ?.&any provisions granting special rights4,to holders of securities upon the occurrence5-of such events as specified in the applicableprospectus supplement;D' l}1DYfVm4 !"#$%&'()*+,-./0123456789:  ?1 )if the debt securities of such series are!!3!+to be issuable in definitive form only upon""0"(receipt of certain certificates or other##6#.documents or satisfaction of other conditions,$$8$0then the form and/or terms of such certificates,%% %documents or conditions;& &?2&*the name of the applicable trustee and the''0'(nature of any material relationship with((7(/us or any of our affiliates, and the percentage))1))of debt securities of the class necessary**.*&to require the trustee to take action;+ +?/+'any deletions from, modifications of or,,7,/additions to our events of default or covenants--/-'with regard to such debt securities and..1.)any change in the right of any trustee or//3/+any of the holders to declare the principal0010)amount of any of such debt securities due111 and payable;2 2?%2applicable CUSIP numbers; and3 3?/3'any other terms of such debt securities44/4'not inconsistent with the provisions of55!5the applicable indenture.67$8____________________________19)Created by Morningstar Document Research.0:(http://documentresearch.morningstar.com/:. cq5Gdy*kW=PF0*8X> @::9988 l  ;  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} I;       Advaxis, Inc. 424B5 01/21/202091Denomination, Interest, Registration and Transfer ?3+issue, register the transfer of or exchange  5 -debt securities of any series during a period  / 'beginning at the opening of business 15  9 1days before the day that the notice of redemption  6 .of any debt securities selected for redemption  5 -is mailed and ending at the close of business#on the day of such mailing; ?0(register the transfer of or exchange any6.debt security, or portion thereof, so selected3+for redemption, in whole or in part, except3+the unredeemed portion of any debt security#being redeemed in part; and ?3+issue, register the transfer of or exchange3+any debt security that has been surrendered2*for repayment at the option of the holder,0(except the portion, if any, of such debt%security not to be so repaid.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/@Dwk_Sgo0Bd{:."=PF0*8X> @ l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} I;       Advaxis, Inc. 424B5 01/21/2020/'Merger, Consolidation or Sale of Assets ?/'either we are the continuing entity, or  / 'the successor entity, if other than us,  8 0assumes the obligations (a) to pay the principal  1 )of, and any premium or make-whole amount,  3 +and interest on, all of the debt securities  2 *and (b) to duly perform and observe all of.&the covenants and conditions containedin each indenture; ?/'after giving effect to the transaction,91there is no event of default under the indentures5-and no event which, after notice or the lapse4,of time, or both, would become such an event-%of default, occurs and continues; and ?2*an officers? certificate and legal opinion.&covering such conditions are delivered#to each applicable trustee.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/>H0ui]r%>g}.e=PF0*8X> @ l  !i  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 8 !      Advaxis, Inc. 424B5 01/21/2020,$Events of Default, Notice and Waiver ?1)default in the payment of any installment  0 (of interest on any debt security of such  & series continuing for 30 days;  ?/ 'default in the payment of principal of,  / 'or any premium or make-whole amount on,  1 )any debt security of such series for five-%business days at its stated maturity; ?2*default in making any sinking fund payment1)as required for any debt security of such&series for five business days; ?/'default in the performance or breach of7/any covenant or warranty in the debt securities0(or in the indenture by us continuing for0(60 days after written notice as provided/'in the applicable indenture, but not of0(a covenant added to the indenture solely6.for the benefit of a series of debt securities1)issued thereunder other than such series; ?2*a default under any bond, debenture, note,*"mortgage, indenture or instrument:$____________________________1)Created by Morningstar Document Research.D~ lxl`8Wy-BY wk_ 0 (http://documentresearch.morningstar.com/H=PF0*8X> @  l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 8       Advaxis, Inc. 424B5 01/21/2020,$Events of Default, Notice and Waiver ?4,in the payment of the principal, any premium  * "or make-whole amount, or interest;  ?7 /in respect of a covenant or provision contained  / 'in the applicable indenture that cannot  2 *be modified or amended without the consent  7 /of the holders of the outstanding debt security+#that is affected by the default; or ?1)in respect of a covenant or provision for1)the benefit or protection of the trustee,,$without its express written consent.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/2xl`u*B_SG=PF0*8X> @ l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 7       Advaxis, Inc. 424B5 01/21/2020,$Events of Default, Notice and Waiver ?5-is in conflict with any law or the applicable    indenture;  ?6 .may involve the trustee in personal liability;   or  ?0 (may be unduly prejudicial to the holders  4 ,of debt securities of the series not joiningthe proceeding.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/,|xl`gW=PF0*8X> @ l  4.4  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} : 4      Advaxis, Inc. 424B5 01/21/2020&Modification of the Indentures ?3+change the stated maturity of the principal  / 'of, or any premium or make-whole amount  1 )on, or any installment of principal of or  , $interest on, any such debt security;  ?0 (reduce the principal amount of, the rate  0 (or amount of interest on, or any premium2*or make-whole amount payable on redemption#of, any such debt security; ?5-reduce the amount of principal of an original1)issue discount security that would be due4,and payable upon declaration of acceleration4,of the maturity thereof or would be provable.&in bankruptcy, or adversely affect any4,right of repayment of the holder of any suchdebt security; ?2*change the place of payment or the coin or0(currency for payment of principal of, or5-any premium or make-whole amount, or interest#on, any such debt security; ?2*impair the right to institute suit for the5-enforcement of any payment on or with respect"to any such debt security; ?1)reduce the percentage in principal amount4,of any outstanding debt securities necessaryD" l~rf~6Oq!7j: !"#$%&'()*+,-./0123  3 +to modify or amend the applicable indenture!!0!(with respect to such debt securities, to""3"+waive compliance with particular provisions##7#/thereof or defaults and consequences thereunder$$6$.or to reduce the quorum or voting requirements%%.%&set forth in the applicable indenture;&& &and' '?.'&modify any of the foregoing provisions((0((or any of the provisions relating to the))8)0waiver of particular past defaults or covenants,**2**except to increase the required percentage++0+(to effect such action or to provide that,,8,0some of the other provisions may not be modified--3-+or waived without the consent of the holder...of such debt security./0$1____________________________12)Created by Morningstar Document Research.03(http://documentresearch.morningstar.com/,|eq'i{'^=PF0*8X> @332211 l  :>ElN  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the IndenturesVoting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} = :      Advaxis, Inc. 424B5 01/21/2020&Modification of the Indentures ?4,to evidence the succession of another person  . &to us as obligor under such indenture;  ?2 *to add to our covenants for the benefit of  ; 3the holders of all or any series of debt securities  4 ,or to surrender any right or power conferred  " upon us in such indenture; ?0(to add events of default for the benefit3+of the holders of all or any series of debt securities; ?7/to add or change any provisions of an indenture/'(i) to change or eliminate restrictions2*on the payment of principal of, or premium2*or make-whole amount, or interest on, debt4,securities in bearer form, or (ii) to permit5-or facilitate the issuance of debt securities-%in uncertificated form, provided that.&such action shall not adversely affect0(the interests of the holders of the debt0(securities of any series in any materialrespect; ?0(to change or eliminate any provisions of3+an indenture, provided that any such change-%or elimination shall become effective:2only when there are no debt securities outstandingD" l~rf|%Jx-A]L !"#$%&'()*+,-./0123456789  1 )of any series created prior thereto which!!6!.are entitled to the benefit of such provision;" "?&"to secure the debt securities;# #?9#1to establish the form or terms of debt securities$$$of any series;% %?4%,to provide for the acceptance of appointment&&0&(by a successor trustee or facilitate the''7'/administration of the trusts under an indenture((!(by more than one trustee;) )?6).to cure any ambiguity, defect or inconsistency**2**in an indenture, provided that such action++0+(shall not adversely affect the interests,,3,+of holders of debt securities of any series--(- issued under such indenture; and. .?1.)to supplement any of the provisions of an//3/+indenture to the extent necessary to permit00.0&or facilitate defeasance and discharge1171/of any series of such debt securities, provided2232+that such action shall not adversely affect3373/the interests of the holders of the outstanding44&4debt securities of any series.56$7____________________________18)Created by Morningstar Document Research.09(http://documentresearch.morningstar.com/8aEi|-L` =PF0*8X> @998877 l  (^)a  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} : (      Advaxis, Inc. 424B5 01/21/2020Voting ?1)the principal amount of an original issue  . &discount security that shall be deemed  0 (to be outstanding shall be the amount of  / 'the principal thereof that would be due  8 0and payable as of the date of such determination  / 'upon declaration of acceleration of thematurity thereof; ?1)the principal amount of any debt security.&denominated in a foreign currency that0(shall be deemed outstanding shall be the-%U.S. dollar equivalent, determined on1)the issue date for such debt security, of2*the principal amount or, in the case of an-%original issue discount security, the0(U.S. dollar equivalent on the issue date6.of such debt security of the amount determined2*as provided in the preceding bullet point; ?3+the principal amount of an indexed security.&that shall be deemed outstanding shall4,be the principal face amount of such indexed-%security at original issuance, unless4,otherwise provided for such indexed security!under such indenture; and ?0(debt securities owned by us or any otherD l~0O{-Nj~.K !"#$%&'  2 *obligor upon the debt securities or by any!!2!*affiliate of ours or of such other obligor"""shall be disregarded.#$$%____________________________1&)Created by Morningstar Document Research.0'(http://documentresearch.morningstar.com/d+=PF0*8X> @''&&%% l  n  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)VotingDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} y<       Advaxis, Inc. 424B5 01/21/20205-Discharge, Defeasance and Covenant Defeasance ?.&a currency, currency unit or composite  6 .currency both by the government of the country  8 0that issued such currency and for the settlement  2 *of transactions by a central bank or other  : 2public institutions of or within the international   banking community; ?.&the European Currency Unit both within0(the European Monetary System and for the91settlement of transactions by public institutions.&of or within the European Communities; or ?/'any currency unit or composite currency1)other than the European Currency Unit for2*the purposes for which it was established.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/:|{ocW fAV0I=1 =PF0*8X> @ l  #S~h  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} I; #      Advaxis, Inc. 424B5 01/21/2020DESCRIPTION OF WARRANTS ?91the number of shares of common stock or preferred  . &stock purchasable upon the exercise of  0 (warrants to purchase such shares and the  0 (price at which such number of shares may  (  be purchased upon such exercise;  ?/ 'the designation, stated value and terms4,(including, without limitation, liquidation,/'dividend, conversion and voting rights)4,of the series of preferred stock purchasable7/upon exercise of warrants to purchase preferredstock; ?/'the principal amount of debt securities0(that may be purchased upon exercise of a/'debt warrant and the exercise price for3+the warrants, which may be payable in cash,%securities or other property; ?91the date, if any, on and after which the warrants2*and the related debt securities, preferred0(stock or common stock will be separately transferable; ?1)the terms of any rights to redeem or call the warrants;Dn lym5U g=Z t&[* !"$ ____________________________1!)Created by Morningstar Document Research.0"(http://documentresearch.morningstar.com/ (=PF0*8X> @""!!  l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 8       Advaxis, Inc. 424B5 01/21/2020DESCRIPTION OF WARRANTS ?3+the date on which the right to exercise the  4 ,warrants will commence and the date on which   the right will expire;  ?7 /U.S. Federal income tax consequences applicable   to the warrants; and  ?7 /any additional terms of the warrants, including3+terms, procedures, and limitations relating0(to the exchange, exercise and settlementof the warrants.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/0}ym?d=PF0*8X> @ l  v  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)BookEntry Delivery and Form!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} 8       Advaxis, Inc. 424B5 01/21/2020DESCRIPTION OF WARRANTS ?.&to vote, consent or receive dividends;  ?3 +receive notice as stockholders with respect  7 /to any meeting of stockholders for the election  0 (of our directors or any other matter; or  ?. &exercise any rights as stockholders of   Advaxis.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/*ihym"3|=PF0*8X> @ l    dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)!BookEntry Delivery and Form (1)PLAN OF DISTRIBUTIONU } $ } $} :       Advaxis, Inc. 424B5 01/21/2020%Book-Entry, Delivery and Form ?/'limited-purpose trust company organized  ' under the New York Banking Law;  ?1 )?banking organization? within the meaning  $ of the New York Banking Law;  ?- %member of the Federal Reserve System;  ?1 )?clearing corporation? within the meaning0(of the New York Uniform Commercial Code; and ?-%?clearing agency? registered pursuant80to the provisions of Section 17A of the Exchange Act.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/4sgJf?yma9=PF0*8X> @ l  ۯ  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and FormPLAN OF DISTRIBUTIONU } $ } $} =       Advaxis, Inc. 424B5 01/21/2020%Book-Entry, Delivery and Form ?6.DTC notifies us that it is unwilling or unable  2 *to continue as a depositary for the global  0 (security or securities representing such  0 (series of securities or if DTC ceases to  1 )be a clearing agency registered under the  2 *Exchange Act at a time when it is required3+to be registered and a successor depositary;3is not appointed within 90 days of the notification7/to us or of our becoming aware of DTC?s ceasing0(to be so registered, as the case may be; ?1)we determine, in our sole discretion, not.&to have such securities represented by)!one or more global securities; or ?:2an Event of Default has occurred and is continuing2*with respect to such series of securities,$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/< sgz.DNq=PF0*8X> @ l  P  dMbP?_*+%,&٭e2?'٭e2?(٭e2?)٭e2?",D/??'!Neither the Securities and Exch PROSPECTUSPROSPECTUS (1)PROSPECTUS (2)PROSPECTUS (3)Company InformationCompany Information (1)!Our stock price can be volatile!We will require additional capi!We will require additional (1)Fees and ExpensesLockUp Agreements EXPERTS!Neither the Securities and (1)!Our stock price can be vola (1)!Our existing and future collabo!Our existing and future col (1)!RATIO OF EARNINGS TO FIXED CHARPreferred StockPreferred Stock (1)Preferred Stock (2) Delaware Law General General (1) General (2)!Denomination Interest Registrat!Merger Consolidation or Sale of!Events of Default Notice and Wa!Events of Default Notice an (1)!Events of Default Notice an (2) Modification of the Indentures Modification of the Indent (1)Voting!Discharge Defeasance and CovenaDESCRIPTION OF WARRANTSDESCRIPTION OF WARRANTS (1)DESCRIPTION OF WARRANTS (2)BookEntry Delivery and Form!BookEntry Delivery and Form (1)U } $ } $} I;       Advaxis, Inc. 424B5 01/21/2020PLAN OF DISTRIBUTION ?91at a fixed price or prices, which may be changed;  ?/ 'at market prices prevailing at the time   of sale;  ?3 +at prices related to such prevailing market    prices; or  ? at negotiated prices.$____________________________1)Created by Morningstar Document Research.0(http://documentresearch.morningstar.com/*;h|pR$=PF0*8X> @ Root Entry FBook  ׺  !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~      !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]